Cart
sales@molnova.com
Butyl isobutyl phthalate
CAS No. 17851-53-5
Butyl isobutyl phthalate( ButylIsobutylPhthalate )
Catalog No. M21572 CAS No. 17851-53-5
Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM)it shows a hypoglycemic effect.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 28 | In Stock |
|
| 25MG | 43 | In Stock |
|
| 50MG | 65 | In Stock |
|
| 100MG | 110 | In Stock |
|
| 500MG | 267 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameButyl isobutyl phthalate
-
NoteResearch use only, not for human use.
-
Brief DescriptionButyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM)it shows a hypoglycemic effect.
-
DescriptionButyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor(IC50 :38 μM)it shows a hypoglycemic effect.
-
In VitroButyl isobutyl phthalate exhibits significant, concentration-dependent inhibitory activity against α-glucosidase with an IC50 value of 38 μM.
-
In VivoButyl isobutyl phthalate (intragastric administration; 25, 50 or 100 mg/kg; 3 days) results in a more significant reduction in the blood glucose level, with the concentration of blood glucose being 11.50, 8.60 and 6.50 mM, respectively. Animal Model:Streptozocin induced diabetic mice (Male Kunming mice)Dosage:25, 50 or 100 mg/kg Administration:Intragastric administration Result:Had the observed antidiabetes activity in mice.
-
SynonymsButylIsobutylPhthalate
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetGlucokinase
-
Recptorα-glucosidase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number17851-53-5
-
Formula Weight278.34
-
Molecular FormulaC16H22O4
-
Purity>98% (HPLC)
-
SolubilityDMSO:250 mg/mL (898.18 mM)
-
SMILESCCCCOC(=O)c1ccccc1C(=O)OCC(C)C
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Bu T Liu M Zheng L et al. α‐glucosidase inhibition and the in vivo hypoglycemic effect of butyl‐isobutyl‐phthalate derived from the Laminaria japonica rhizoid[J]. Phytotherapy Research 2010 24(11).
molnova catalog
related products
-
Kaempferol 3-gentiob...
Kaempferol 3-O-gentiobioside is a flavonoid isolated from C. alata leaves with antidiabetic activity. It possesses activity against α-glucosidase and displays a carbohydrate enzyme inhibitory effect (IC50: 50 μM).
-
AZD-1656
AZD-1656 is a glucokinase activator (GKA) that can cause dose-limiting hypoglycemia in normal animals used in embryofetal development studies and type 2 diabetes.
-
POMHEX
Pomhex, a cell-permeable potent enolase inhibitor with anticancer activity, is used in the study of cancer lethality.Pomhex, a racemic mixture, is a potent and selective ENO2 inhibitor.
